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Conoa-B announced that the CMG901 global phase III clinical trial Clarity-Gastric01 in collaboration with AstraZeneca achieved positive top-line results. Compared with the treatment plan selected by the researchers, CMG901 showed a statistically significant and clinically significant improvement in overall survival in second-line and late-line CLDN18.2-positive advanced gastric cancer patients. The trial reached both primary endpoints for third-line and post-line treatment OS and key secondary OS endpoints for second-line and post-line treatment in the overall trial population; PFS showed an improvement trend but was not statistically significant. The safety characteristics are consistent with what is known, and no new safety signals have been found.
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Conoa-B announced that the CMG901 global phase III clinical trial Clarity-Gastric01 in collaboration with AstraZeneca achieved positive top-line results. Compared with the treatment plan selected by the researchers, CMG901 showed a statistically significant and clinically significant improvement in overall survival in second-line and late-line CLDN18.2-positive advanced gastric cancer patients. The trial reached both primary endpoints for third-line and post-line treatment OS and key secondary OS endpoints for second-line and post-line treatment in the overall trial population; PFS showed an improvement trend but was not statistically significant. The safety characteristics are consistent with what is known, and no new safety signals have been found.
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