This is an initial public offering of shares of common stock of Latigo Biotherapeutics, Inc. We are offering 16,000,000 shares of our common stock to be sold in this offering.

Prior to this offering, there has been no public market for our common stock. The initial public offering price is expected to be between $16.00 and $18.00 per share. We have applied to list our common stock on The Nasdaq Global Select Market under the symbol "LTGO".

We are an "emerging growth company" and a "smaller reporting company" as defined under the U.S. federal securities laws and, as such, have elected to comply with certain reduced public company reporting requirements.

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