Highlights:

MINNEAPOLIS, Aug. 31, 2026 /PRNewswire/ -- To help clinicians determine which medications may be most effective at preventing migraine in adults, the American Academy of Neurology (AAN) and American Headache Society (AHS) have issued a joint practice guideline update with evidence-based recommendations, published on August 31, 2026, in Neurology^®, the medical journal of the American Academy of Neurology, and in Headache, the official journal of the American Headache Society. This is an update to the AAN and AHS 2012 guideline. The guideline is endorsed by the American Academy of Family Physicians.