First, HPV vaccination before the probability of HPV infection increases, that is, before the first sexual activity occurs, can maximize the vaccine's role in preventing HPV infection and obtain better protective effects. Second, domestic and foreign studies have shown that the level of antibodies produced by girls aged 9 to 14 receiving the HPV vaccine is more than 2 times that of people aged 15 and over, and the protective effect lasts at least 10 years. If you get vaccinated at age 13, you can get higher levels of antibodies and longer lasting protection. Third, many countries give school-age girls the HPV vaccine free of charge, and most target groups are 11 to 13 years old. Previously, provinces such as Guangdong, Jiangxi, and Hainan provided free HPV vaccination for middle school age girls through livelihood programs, etc., covering more than 10 million people, verifying the viability of using 13-year-old girls as vaccination targets.

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