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NovaBridge’s Visara Plans To Develop HT006.2.2 As VIS-102, Second Clinical-Stage Program, Expanding Its Ophthalmology Portfolio Beyond Retinal Vascular Disease Into Ocular Surface Disease
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Visara secures exclusive worldwide rights, excluding Greater China, from Wuhan Hiteck Biological Pharma to develop and commercialize HT006.2.2

Visara plans to develop HT006.2.2 as VIS-102, its second clinical-stage program, expanding the Company's ophthalmology portfolio beyond retinal vascular disease into ocular surface disease

HT006.2.2 is designed to offer a more convenient treatment option for patients with neurotrophic keratitis

ROCKVILLE, Md., Oct. 13, 2026 (GLOBE NEWSWIRE) -- Visara, Inc. ("Visara" or the "Company"), a majority-owned ophthalmology subsidiary of NovaBridge Biosciences ("NovaBridge") (NASDAQ:NBP), today announced that it has entered into an exclusive license agreement (the "License Agreement") with Wuhan Hiteck Biological Pharma Co., Ltd. ("Hiteck") for the development and commercialization of VIS-102 (HT006.2.2), an investigational next-generation modified recombinant human nerve growth factor (rhNGF) therapy designed to restore corneal health in patients with neurotrophic keratitis (NK).

In NK, damage to the corneal nerves impairs the eye's ability to heal. This can lead to persistent epithelial defects, corneal ulceration and permanent vision loss. VIS-102 is designed to restore corneal health with a more convenient treatment option for patients. In addition to formulation optimization, it incorporates targeted modifications to the NGF amino acid sequence intended to improve resistance to enzymatic degradation and maintain stability under refrigeration. These changes allow VIS-102 to potentially be supplied in ready-to-use, single-dose units. This design may reduce the storage, shipping, handling and administration burden associated with current treatments for NK.

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