Plaza Companies and Fayth Hospitality will break ground on Hotel Six Four, Mayo Blvd, a new 257-room dual-brand Hilton hotel at the southeast corner of 64th Street and Mayo Boulevard in North Phoenix.

The six-story hotel will combine the boutique lifestyle experience of Tapestry Collection by Hilton with the extended-stay accommodations of Homewood Suites by Hilton.

The property is less than one mile from Mayo Clinic’s Phoenix campus and near the new Brooks Rehabilitation Hospital, ASU’s Health Futures Center and the developing Discovery Oasis biotechnology campus, placing it at the center of a growing healthcare and bioscience ecosystem.

A signature first-floor restaurant and bar will offer indoor, outdoor and private dining for both hotel guests and the surrounding community. The hotel will include significant amenities as well, such as a pool, gym, meeting space and much more. 

Mayse & Associates is serving as architect and EBCO General Contractor is the general contractor.

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