NEW YORK, Nov. 4, 2026 /PRNewswire/ -- Fly on Wall Street News Commentary - Wall Street's major indexes rallied together on Wednesday. As of 2:31 p.m. ET, the Dow Jones Industrial Average was up 1,552.12 points, or 3.0%, at 53,338.84, while the S&P 500 was up 1.8% at 7,702.43 and the Nasdaq Composite was up 1.8% at 25,839.48. Active Companies from around the markets with current developments this week include: Amgen Inc. (NASDAQ: AMGN), Gilead Sciences, Inc. (NASDAQ: GILD), Vertex Pharmaceuticals Incorporated (NASDAQ: VRTX), Incyte Corporation (NASDAQ: INCY), and Merck & Co., Inc. (NYSE: MRK).